CG Vyapam Pharmacist Grade‑2 — Mock Test Question Paper

CG Vyapam Pharmacist Grade‑2 — Mock Test Question Paper

CG Vyapam Pharmacist Grade-2

Full-Length Mock Test Paper (100 Questions | PYQ-Based)

Time: 2 Hours
Total Questions: 100
Marks: 100

🔬 PHARMACEUTICS (Q1–25)

Q1. Bioavailability is defined as:
A. Rate of metabolism
B. Fraction of drug reaching systemic circulation
C. Drug excretion rate
D. Protein binding

Q2. Which factor affects dissolution rate most?
A. Particle size
B. Color
C. Odor
D. Shape

Q3. Which is a diluent?
A. Talc
B. Lactose
C. Magnesium stearate
D. Gelatin

Q4. First-pass metabolism occurs in:
A. Kidney
B. Liver
C. Brain
D. Heart

Q5. Which route avoids first-pass effect?
A. Oral
B. Rectal
C. Sublingual
D. Intraperitoneal

Q6. Emulsifying agent example:
A. Gum acacia
B. Talc
C. Starch
D. Sucrose

Q7. Bulk density measures:
A. Flow property
B. Packing ability
C. Particle shape
D. Surface tension

Q8. Disintegrant works by:
A. Binding
B. Swelling
C. Lubrication
D. Coloring

Q9. Which sterilization uses dry heat?
A. Autoclave
B. Hot air oven
C. Filtration
D. Radiation

Q10. Isotonic solution example:
A. 0.9% NaCl
B. 5% NaCl
C. 10% NaCl
D. Distilled water

Q11. Partition coefficient relates to:
A. Solubility
B. Lipid solubility
C. Stability
D. Density

Q12. Suspension stability depends on:
A. Sedimentation rate
B. Color
C. Taste
D. Smell

Q13. Which is lubricant?
A. Talc
B. Lactose
C. Starch
D. Gelatin

Q14. Which dosage form is sterile?
A. Tablets
B. Capsules
C. Injection
D. Syrup

Q15. pH affects:
A. Color
B. Stability
C. Size
D. Shape

Q16. Bioequivalence compares:
A. Structure
B. Absorption rate & extent
C. Toxicity
D. Price

Q17. Which is preservative?
A. Paraben
B. Lactose
C. Talc
D. Starch

Q18. Angle of repose measures:
A. Density
B. Flow
C. Stability
D. Size

Q19. Granulation improves:
A. Taste
B. Flow
C. Color
D. Smell

Q20. Controlled release aims to:
A. Rapid action
B. Sustained effect
C. Toxicity
D. Elimination

Q21. Syrup contains:
A. Alcohol
B. Sugar
C. Oil
D. Acid

Q22. Which method sterilizes heat-sensitive drugs?
A. Autoclave
B. Filtration
C. Hot air oven
D. Boiling

Q23. Which is plasticizer?
A. PEG
B. Talc
C. Lactose
D. Starch

Q24. Ointment base type:
A. Hydrocarbon
B. Alcohol
C. Acid
D. Salt

Q25. Drug absorption mainly occurs in:
A. Stomach
B. Small intestine
C. Colon
D. Esophagus

💊 PHARMACOLOGY (Q26–50)

Q26. β1 selective blocker:
A. Propranolol
B. Atenolol
C. Timolol
D. Nadolol

Q27. Dopamine deficiency causes:
A. Alzheimer’s
B. Parkinson’s
C. Epilepsy
D. Depression

Q28. Antidote for opioid overdose:
A. Naloxone
B. Atropine
C. Diazepam
D. Warfarin

Q29. Therapeutic index =
A. ED50/LD50
B. LD50/ED50
C. TD50/ED50
D. ED99/TD1

Q30. Tachyphylaxis means:
A. Slow response
B. Rapid tolerance
C. Allergy
D. Toxicity

Q31. Which is NSAID?
A. Aspirin
B. Penicillin
C. Insulin
D. Diazepam

Q32. Insulin is used in:
A. Diabetes
B. Hypertension
C. Asthma
D. Fever

Q33. GABA agonist drug:
A. Diazepam
B. Paracetamol
C. Atenolol
D. Metformin

Q34. Warfarin acts as:
A. Anticoagulant
B. Antibiotic
C. Analgesic
D. Antipyretic

Q35. Histamine causes:
A. Vasodilation
B. Vasoconstriction
C. No effect
D. Paralysis

Q36. Atropine blocks:
A. Nicotinic
B. Muscarinic
C. Dopamine
D. GABA

Q37. Adrenaline acts on:
A. α & β receptors
B. Only α
C. Only β
D. None

Q38. Paracetamol is:
A. Analgesic
B. Antibiotic
C. Antifungal
D. Antiviral

Q39. Morphine causes:
A. CNS stimulation
B. CNS depression
C. No effect
D. Seizures

Q40. Penicillin acts on:
A. Cell wall
B. DNA
C. RNA
D. Protein

Q41. Drug tolerance means:
A. Increased response
B. Decreased response
C. Allergy
D. Toxicity

Q42. Antihistamines treat:
A. Allergy
B. Diabetes
C. Hypertension
D. Infection

Q43. Local anesthetic example:
A. Lidocaine
B. Aspirin
C. Morphine
D. Atropine

Q44. Beta blockers treat:
A. Hypertension
B. Infection
C. Diabetes
D. Pain

Q45. Antibiotics act against:
A. Virus
B. Bacteria
C. Fungi
D. Worms

Q46. CNS stimulant:
A. Caffeine
B. Morphine
C. Diazepam
D. Insulin

Q47. Antipyretic reduces:
A. Pain
B. Fever
C. BP
D. Sugar

Q48. Vaccine provides:
A. Passive immunity
B. Active immunity
C. No immunity
D. Temporary relief

Q49. Diuretics increase:
A. Urine output
B. BP
C. Sugar
D. Weight

Q50. Antacid neutralizes:
A. Base
B. Acid
C. Salt
D. Water

⚗️ PHARMACEUTICAL CHEMISTRY (Q51–70)

Q51. β-lactam ring present in:
A. Penicillin
B. Aspirin
C. Paracetamol
D. Ibuprofen

Q52. Blood pH:
A. 6.8
B. 7.4
C. 8.0
D. 5.0

Q53. Alkaloid example:
A. Morphine
B. Glucose
C. Urea
D. Citric acid

Q54. Oxidation is:
A. Gain of electrons
B. Loss of electrons
C. Gain of H
D. Loss of O

Q55. Buffer in blood:
A. Acetate
B. Bicarbonate
C. Citrate
D. Phosphate

Q56. Isomerism means:
A. Same formula diff structure
B. Same structure
C. Diff formula
D. None

Q57. Acid pH:
A. <7
B. >7
C. 7
D. 10

Q58. Base pH:
A. <7
B. >7
C. 7
D. 5

Q59. Sodium chloride is:
A. Acid
B. Base
C. Salt
D. Alcohol

Q60. Covalent bond involves:
A. Electron sharing
B. Electron transfer
C. Proton transfer
D. Neutron

Q61. Alcohol group:
A. -OH
B. -COOH
C. -NH2
D. -CHO

Q62. Ketone group:
A. -CO-
B. -OH
C. -NH2
D. -COOH

Q63. Molecular weight unit:
A. g/mol
B. kg
C. m
D. sec

Q64. Avogadro number:
A. 6.023×10²³
B. 3×10⁸
C. 9.8
D. 1.6×10⁻¹⁹

Q65. Strong acid example:
A. HCl
B. CH3COOH
C. NH3
D. NaOH

Q66. Weak base:
A. NH3
B. NaOH
C. HCl
D. H2SO4

Q67. pKa relates to:
A. Acidity
B. Density
C. Color
D. Weight

Q68. Hydrolysis involves:
A. Water
B. Air
C. Heat
D. Light

Q69. Organic compound contains:
A. Carbon
B. Oxygen
C. Nitrogen
D. Hydrogen

Q70. Catalyst does:
A. Increase rate
B. Decrease rate
C. No effect
D. Stop reaction

🌿 PHARMACOGNOSY (Q71–85)

Q71. Clove is:
A. Flower bud
B. Leaf
C. Root
D. Bark

Q72. Digitalis from:
A. Leaf
B. Root
C. Seed
D. Stem

Q73. Alkaloids are:
A. Basic
B. Acidic
C. Neutral
D. Salt

Q74. Cinchona gives:
A. Morphine
B. Quinine
C. Atropine
D. Codeine

Q75. Senna is:
A. Laxative
B. Analgesic
C. Antipyretic
D. Antibiotic

Q76. Aloe used as:
A. Laxative
B. Antibiotic
C. Analgesic
D. Sedative

Q77. Volatile oils are:
A. Aromatic
B. Solid
C. Tasteless
D. Odorless

Q78. Tannins are:
A. Astringent
B. Sweet
C. Bitter
D. Sour

Q79. Glycosides contain:
A. Sugar
B. Protein
C. Fat
D. Mineral

Q80. Crude drug means:
A. Natural form
B. Synthetic
C. Chemical
D. Pure

Q81. Opium from:
A. Latex
B. Leaf
C. Root
D. Bark

Q82. Menthol source:
A. Mint
B. Neem
C. Tulsi
D. Aloe

Q83. Resins are:
A. Solid
B. Liquid
C. Gas
D. Crystal

Q84. Herbal drugs are:
A. Plant-based
B. Animal
C. Synthetic
D. Mineral

Q85. Pharmacognosy studies:
A. Natural drugs
B. Synthetic drugs
C. Surgery
D. Pathology

🏥 HOSPITAL PHARMACY + GENERAL (Q86–100)

Q86. b.i.d means:
A. Once
B. Twice
C. Thrice
D. Four

Q87. IV route gives:
A. Slow effect
B. Fast effect
C. No effect
D. Delayed

Q88. Bioavailability 100% in:
A. Oral
B. IV
C. IM
D. SC

Q89. Kidney function:
A. Excretion
B. Digestion
C. Respiration
D. Circulation

Q90. Normal temp:
A. 37°C
B. 35°C
C. 39°C
D. 40°C

Q91. SI unit pressure:
A. Pascal
B. Joule
C. Watt
D. Newton

Q92. DNA full form:
A. Deoxyribonucleic acid
B. Dinucleic
C. Double acid
D. None

Q93. Insulin produced by:
A. Liver
B. Pancreas
C. Kidney
D. Heart

Q94. Vitamin C deficiency:
A. Scurvy
B. Rickets
C. Beriberi
D. Pellagra

Q95. ECG measures:
A. Heart activity
B. Brain
C. Kidney
D. Liver

Q96. Dose calc 500 mg/5 ml =
A. 100 mg/ml
B. 50 mg/ml
C. 10 mg/ml
D. 500 mg/ml

Q97. Half-life concept:
A. Time to eliminate half drug
B. Full drug
C. Double drug
D. None

Q98. Isotonic solution:
A. 0.9% NaCl
B. 5% NaCl
C. 10% NaCl
D. Water

Q99. Pharmacokinetics:
A. Drug movement
B. Drug action
C. Drug structure
D. Drug source

Q100. Pharmacodynamics:
A. Drug effect
B. Drug movement
C. Drug synthesis
D. Drug storage

✅ FINAL ANSWER KEY

QAnsQAnsQAnsQAnsQAns
1B21B41B61A81A
2A22B42A62A82A
3B23A43A63A83A
4B24A44A64A84A
5C25B45B65A85A
6A26B46A66A86B
7B27B47B67A87B
8B28A48B68A88B
9B29B49A69A89A
10A30B50B70A90A
11B31A51A71A91A
12A32A52B72A92A
13A33A53A73A93B
14C34A54B74B94A
15B35A55B75A95A
16B36B56A76A96A
17A37A57A77A97A
18B38A58B78A98A
19B39B59C79A99A
20B40A60A80A100A